The score was scoreless after the first period, and tied, 1-1, after the second, when Buffalo outscored New Jersey, 3-2, in the final period.
Daniel Paille and Ales Kotalik scored once each; Dmitri Kalinin had two assists; and Ryan Miller made 28 saves on 31 shots for the Sabres, who have 105 points and a comfortable seven-point lead over the Devils for first place in the East.
Kotalik had missed the previous 16 games with a knee injury, and Paille missed 15 games with a hand injury.
The Sabres pulled even with Nashville for most points in the league.
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