The basket came after an alley-oop pass from Hedo Turkoglu.
San Antonio blew a 59-48 halftime lead. The teams entered the fourth quarter tied at 80-80, and were close the entire fourth quarter.
Jameer Nelson led Orlando with 31 points, seven rebounds and five assists. Howard had 30 points, eight rebounds, four steals and three blocked shots; and Carlos Arroyo came off the bench to add 12 points and seven assists for the Magic, who broke a three-game losing streak.
Tim Duncan led San Antonio with 24 points and 16 rebounds, and Brent Barry scored 21 points. Michael Finley totaled 18 points, two rebounds, two steals and two blocks; while Tony Parker added 17 points and seven assists for the Spurs, who dropped to 2-3 on an eight-game road trip.