The four-year veteran from Baylor established an NFL record in Sunday's 48-20 rout of Denver -- scoring three touchdowns for an NFL single-season record 29 TDs.
Seattle's Shaun Alexander scored 28 touchdowns in his 2005 MVP season.
Tomlinson was joined by Buffalo end Aaron Schobel (defense), and Jacksonville running back/kick returner Maurice Jones-Drew (Special Teams) as this week's AFC player honorees.
Schobel had three sacks and nine tackles, and forced a fumble as the Bills surprised the New York Jets, 31-13.
Jones-Drew scored three touchdowns -- including a 93-yard kickoff return to open the second half -- in Jacksonville's 44-17 win over the AFC South-leading Indianapolis.
He recorded a franchise-record 303 all-purpose yards to surpass the 291 yards compiled by Jimmy Smith in 2000 against Baltimore.