Whitworth rushed 13 times for 118 yards and one touchdown, and Callender had 105 yards and a TD on 15 carries.
Boston College's Matt Ryan was 23-for-37 for 219 yards, with two touchdown passes and one interception for the Eagles (8-2, 4-2 ACC).
Clifford Harris led the Blue Devils rushing attack, with 69 yards and a touchdown on six carries. Thaddeus Lewis completed 20-of-40 pass attempts, and threw two interceptions for Duke (0-10, 0-6), which remained winless on the season.
Notable deaths of 2014 [PHOTOS]