Casey Dick completed 11-of-19 passes for 228 yards and a touchdown for the Razorbacks (8-1, 5-0 SEC), who won for the eighth straight time, after a season opening loss to Southern California.
Marcus Monk caught eight passes for 192 yards and a touchdown for Arkansas.
Backup quarterback Blake Mitchell was 15-of-21 for 213 yards with two touchdowns and an interception for the Gamecocks (5-4, 3-4), who lost their second straight game, and still need one more win to become bowl eligible.
Jordana Brewster on Paul Walker: 'He was an enormous presence in my life'
Couple mistakenly served bag of cash at McDonald's drive-thru