Anthony Roberson scored a career-high 14 points; Dahntay Jones had 13 points, four rebounds and two assists; and Cardinal sank two huge three-pointers in the extra session for the Grizzlies (49-33).
Memphis goes into the Western Conference playoffs as the No. 5 seed after a season-ending five-game winning streak. The Grizzlies, who will face fourth-seeded Dallas in the first round, went 8-1 in April. Star players Pau Gasol and Eddie Jones sat out the contest to avoid injury.
Bracey Wright had 19 points and four rebounds; Eddie Griffin added 17 points and 15 rebounds; and Marcus Banks totaled 15 points, six rebounds, two assists and three steals for the Timberwolves (33-49), who closed the season with a three-game losing streak and will miss the playoffs for the second straight season.