Federer, who is 30-1 this year, is the current Wimbledon, U.S. Open and Australian Open champion as well as the winner of the two Masters Series tournaments this season -- Indian Wells and Miami.
Monte-Carlo is the third Masters of the nine played.
No. 3 David Nalbandian of Argentina and No. 4 Ivan Ljubicic of Croatia also won their second-round contests.
No. 6 Guillermo Coria of Argentina, the 2004 Monte-Carlo champion and 2003 and 2005 runner-up also moved to the third round, The Sports Network reports.
The winner of the tournament earns $418,000.
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