Rob Bowen drove in two runs while Josh Barfield added three hits and scored two runs for the Padres, who snapped a four-game losing streak with their first win since an opening day victory against San Francisco.
Woody Williams (1-0) pitched five innings and allowed three runs on five hits in his first start of the season. Williams was plugged into the starting rotation in place of Shawn Estes after he was placed on the 15-day disabled list with a strained left elbow.
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