The 14th-ranked Huskies began the game with a 21-3 run, led by 11 at the half and scored a dozen straight points early in the second period.
Washington improved to 14-2 and to 4-1 in the Pac-10.
Oregon (10-3, 2-2) was led by Bryce Taylor with 16. It was the 16th straight home win for the Huskies.
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