Moya beat Croatian wild card Roko Karanusic 6-4, 6-4.
The former world No. 1 Moya bested Italian Filippo Volandri in last year's final to secure a third straight and fourth overall title here.
Three other seeds reached the second round this week, as Spaniard Alberto Martin outlasted Jerome Golmard of France 6-2, 4-6, 6-2, Argentine Guillermo Canas defeated Frenchman Olivier Patience 6-3, 6-2 and No. 7 Brazilian Flavio Saretta beatd Swiss Stanislas Wawrinka 6-3, 6-1.