Houston went ahead 2-0 in the third inning on a two-run home run by Craig Biggio. The Dodgers tied it on an RBI single by Jayson Werth in the fourth and went ahead on a single by Jackson, the first hit of his career.
Lo Duca hit a solo homer in the fifth inning.
Jackson (2-0) allowed five hits and two runs in five innings nd Giovanni Carrara, Darren Dreifort and Tom Martin pitched in relief for Los Angeles.
Brandon Duckworth (1-2) took the loss.