Manning, the AFC Offensive Player of the Month, did nearly a month's work in one night, passing for six touchdowns in the Indianapolis Colts' 55-21 win over New Orleans last Sunday. The last quarterback to throw six touchdowns in one game was Washington's Mark Rypien on Nov. 10, 1991.
The Colts were 4-0 last month, and Manning passed for 914 yards and nine touchdowns.
Culpepper, the NFC Offensive Player of the Month, led the Minnesota Vikings to three of their four wins in a 4-0 September. He completed 42-of-69 passes for 514 yards and five touchdowns with no interceptions for a 108.0 passer rating, second-highest in the NFL.
Others honored were Kansas City's Dante Hall, who had three kick returns for touchdown, cornerback Marcus Coleman of Houston, defensive end Mike Rucker of Carolina, and placekicker Jeff Wilkins of St. Louis.