Last week, Toledo (3-1) snapped Marshall's 17-game home winning streak, a victory that looks even better after the Thundering Herd won at No. 6 Kansas State on Saturday afternoon.
Gradkowski, a sophomore making his fourth career start, was 49-of-62 for 461 yards, all school records, and had three passes. His nine-yard scoring toss to Lance Moore with 43 seconds left gave the Rockets their first lead.
"I'm so pumped about this team that words can't express what I feel right now," said Gradkowski, ironically a native of Pittsburgh. "If you believe in yourself, there is no telling what can happen."
Toledo trailed, 31-21, before Trinity Dawson's two-yard touchdown run with 6:45 to play.
"Their offense really gave our defense all sorts of problems," said Pittsburgh Coach Walt Harris. "Their quarterback did a fabulous job and their receivers caught everything."
Panthers quarterback Rod Rutherford, who entered the contest with the nation's best pass efficiency rating, completed 24-of-36 passes for 315 yards, four touchdowns, and two interceptions for Pittsburgh (2-1).
2014: The Year in Music [PHOTOS]