Hossa tied the game at 1-1 midway through the first period and made it 4-2 early in the third. With six goals in his last three contests, he has 27 for the season, one behind Vancouver's Markus Naslund for the NHL lead.
Todd White, Magnus Arvedson and Petr Schastlivy also scored for Ottawa, which won for the 20th time in its last 28 games (20-3-4-1) and improved the league's best record to 25-9-5-1.
The Senators improved to 2
The Rangers don't have such problems, but they can't win. With the highest payroll in the NHL, they fell to 3-9-2-1 since hitting the break-even mark on Dec. 3.
Already without seven injured regulars, New York lost right wing Ronald Petrovicky to a sprained ankle and left wing Gordie Dwyer to a strained hamstring.