Faulk's second touchdown 9:41 into the second half moved him past John Riggins and into seventh place on the NFL's all-time list. Faulk finished the contest with 119 career touchdowns.
With his fourth carry of the second half, a 10-yard run up the middle, Faulk became the 15th player in NFL history to rush for 10,000 yards in his career.
"Right now, it doesn't matter much," Faulk said of the milestones. "When you look back on your career, you think of numbers. It's nice to have them."
The Rams (2-5) were winless entering last weekend when Faulk ran for 158 yards and caught a 10-yard touchdown pass to help lift St. Louis over a then-unbeaten Oakland club. Then, the six-time Pro Bowler led the defending NFC champion to victory again on Sunday.
"We're winning ballgames again, although we had a tough start," Faulk said. "You've got to make adjustments in this business. The teams that make the adjustments quickest succeed."
The 2000 MVP when he set an NFL record with 26 touchdowns, Faulk recorded his fifth career four-touchdown performance. He last accomplished the feat on Dec. 30, 2001 against Indianapolis.
"This is the Rams team I think we're all used to seeing," Coach Mike Martz said. "We gave Marshall the game ball for his effort today. That's a remarkable performance. Go back and just look at how many times it's been done in the NFL."
Seattle struggled offensively throughout the game. Trent Dilfer completed just eight of 25 passes with two interceptions and Shaun Alexander was limited to 30 yards on 12 carries as the Seahawks (1-5) lost for the sixth time in eight all-time meetings with the Rams.
"Too much Marshall Faulk today," Seahawks Coach Mike Holmgren said. "He's really a great player and what a day he had. He's hard to tackle and he plays the game with great speed."
Dilfer was knocked out of the game with 3:28 to play, when safety Adam Archuleta was penalized for roughing the passer.
"There's nothing broken like my pride is," Dilfer said. "I'm going to be fine. My jaw and elbow are a little sore. I got banged around pretty good, but that's how it goes."
Meanwhile, the Rams suffered another devastating injury. With star quarterback Kurt Warner already sidelined, seven-time Pro Bowl cornerback Aeneas Williams was carted off the field with 1:46 left with a broken left fibula and sprained left ankle.
"The fibula will heal on its own," Rams trainer Jim Anderson said. "The ankle will need to be surgically repaired. We will probably do surgery tonight. Any kind of speculations we don't have yet. We'll be able to give a more accurate date as far as his recovery after the surgery."
On St. Louis' second possession of the game, Faulk carried the ball five times for 24 yards. Then, the star running back capped the 10-play, 62-yard drive with a six-yard touchdown catch to make it 7-0.
Faulk ran the ball six times on the Rams' 13-play, 80-yard drive that used up 7:54 of the third quarter. He finished it off with a three-yard touchdown run up the middle to put St. Louis ahead for good, 20-14.
Faulk also scored on runs of two yards and one yard in a 6:07 span of the final quarter.
Koren Robinson was the lone bright spot for Seattle, recording three catches for 166 yards. The receiver had a 79-yard touchdown grab and an 83-yard reception.
"I don't know how I let (Rams cornerback Travis Fisher) catch me," Robinson said. "I should have had a second touchdown. We've got to come out with a win some kind of way."