Favre found Donald Driver with a 21-yard scoring strike to give Green Bay the lead for good at 10-7 in the first quarter. The Packers looked to have another score in the second quarter but an apparent 39-yard TD pass from Favre to Charles Lee was nullified by offensive pass interference.
Walker had a 30-yard reception which helped set up a 25-yard field goal by Ryan Longwell that provided a six-point halftime cushion.
Backup quarterback Doug Pederson found Lee for a 39-yard touchdown and a 20-7 lead in the third. Green Bay then took advantage of Cardinals' rookie quarterback Josh McCown for its next nine points. McCown lost the ball through the end zone for a safety and had a deflected pass intercepted by linebacker Torrance Marshall, who ran it back 18 yards for a touchdown and a 29-7 advantage.
McCown was not the only quarterback to have a rough outing for Arizona as Chris Griesen, the leading candidate for the backup job behind Jake Plummer, was 4-for-13 for 61 yards and an interception. The Packers registered seven sacks.
Arizona recovered a fumble by Ahman Green at the Packers' 22-yard-line that led to a two-yard touchdown run by Thomas Jones for a 7-0 lead in the first quarter. That was the lone highlight for Jones, who carried seven times for two yards and fumbled once.
Pederson completed 10-of-14 passes for 121 yards.
Plummer played just the first quarter and completed 4-of-8 passes for 56 yards. The Cardinals scored their final two touchdowns in the fourth quarter on a 74-yard pass from Preston Parsons to Jason McCaddley and a one-yard plunge by rookie Damien Anderson.