1.
Johnny Tapia, boxing champ, dead at 45

| Sunday, November 1, 2009 | |||||
| Final | 1 | 2 | 3 | 4 | Score |
| San Francisco | 7 | 7 | 0 | 0 | 14 |
| Indianapolis | 3 | 6 | 3 | 6 | 18 |
| Wrap | |||||
| Scoring Summary |
| First Quarter |
| San Francisco Touchdown - 64-yard run by Frank Gore. (Joe Nedney extra point is good). |
| Indianapolis Field Goal - 38-yarder by Matt Stover. |
| Second Quarter |
| Indianapolis Field Goal - 33-yarder by Matt Stover. |
| San Francisco Touchdown - 8-yard pass from Alex Smith to Vernon Davis. (Joe Nedney extra point is good). |
| Third Quarter |
| Indianapolis Field Goal - 40-yarder by Matt Stover. |
| Fourth Quarter |
| Indianapolis Touchdown - 22-yard pass from Joseph Addai to Reggie Wayne. (Peyton Manning pass incomplete to Reggie Wayne, two-point conversion failed). |
| Final Team Statistics | ||
| Statistics | San Francisco | Indianapolis |
| First Downs | 16 | 20 |
| Rushes-yards | 18-113 | 21-61 |
| Passing yards | 198 | 369 |
| Return yards | 182 | 349 |
| Passing (Att-Comp-Int) | 32-19-1 | 49-32-0 |
| Punts-Average | 8-50.0 | 7-46.3 |
| Penalties-Yards | 7-50 | 5-38 |
| Time of Possession | 26:26 | 33:34 |
| Individual Statistics | |
| Rushing | |
| San Francisco | Frank Gore 13-91, Alex Smith 1-10, Glen Coffee 1-8, Moran Norris 3-4 |
| Indianapolis | Joseph Addai 20-62, Chad Simpson 1--1 |
| Passing | |
| San Francisco | Alex Smith (19-32), Yards: 198, Sacked: 4, TD: 1 |
| Indianapolis | Peyton Manning (31-48), Yards: 347, Sacked: 3, TD: 0, Joseph Addai (1-1), Yards: 22, Sacked: 0, TD: 1 |
| Receiving | |
| San Francisco | Michael Crabtree 6-81, Frank Gore 5-43, Isaac Bruce 4-51, Vernon Davis 3-20, Josh Morgan 1-3 |
| Indianapolis | Reggie Wayne 12-147, Dallas Clark 8-99, Austin Collie 6-66, Pierre Garcon 4-53, Joseph Addai 2-4 |
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