| Scoring Summary |
| First Quarter |
| San Diego Touchdown - 11-yard pass from Philip Rivers to Brandon Manumaleuna. (Nate Kaeding extra point is good). |
| Tampa Bay Touchdown - 1-yard run by B.J. Askew. (Matt Bryant extra point is good). |
| Second Quarter |
| San Diego Touchdown - 15-yard pass from Philip Rivers to Antonio Gates. (Nate Kaeding extra point is good). |
| San Diego Field Goal - 28-yarder by Nate Kaeding. |
| Third Quarter |
| Tampa Bay Touchdown - 7-yard run by Jeff Garcia. (Matt Bryant extra point is good). |
| Tampa Bay Touchdown - 71-yard pass from Jeff Garcia to Antonio Bryant. (Matt Bryant extra point is good). |
| Fourth Quarter |
| San Diego Touchdown - 5-yard pass from Philip Rivers to Antonio Gates. (Nate Kaeding extra point is good). |
| San Diego Touchdown - 32-yard pass from Philip Rivers to Darren Sproles. (Nate Kaeding extra point is good). |
| Individual Statistics |
| Rushing |
| San Diego |
LaDainian Tomlinson 21-90, Darren Sproles 2-3, Philip Rivers 3--3 |
| Tampa Bay |
Jeff Garcia 6-45, Carnell Williams 8-27, Warrick Dunn 9-20, Luke McCown 2-16, Clifton Smith 1-2, B.J. Askew 1-1 |
| Passing |
| San Diego |
Philip Rivers (21-31), Yards: 287, Sacked: 1, TD: 4 |
| Tampa Bay |
Jeff Garcia (21-35), Yards: 232, Sacked: 2, TD: 1 |
| Receiving |
| San Diego |
Vincent Jackson 7-111, Antonio Gates 4-43, Darren Sproles 3-46, Legedu Naanee 2-29, Chris Chambers 2-27, LaDainian Tomlinson 2-20, Brandon Manumaleuna 1-11 |
| Tampa Bay |
Antonio Bryant 6-127, Ike Hilliard 4-24, Warrick Dunn 4-19, Michael Clayton 2-23, Jerramy Stevens 2-21, Clifton Smith 1-9, B.J. Askew 1-5, Joey Galloway 1-4 |
