1.
Tommie Harris' wife dies

| Sunday, November 16, 2008 | |||||
| Final | 1 | 2 | 3 | 4 | Score |
| San Diego | 7 | 0 | 0 | 3 | 10 |
| Pittsburgh | 0 | 5 | 3 | 3 | 11 |
| Wrap | |||||
| Scoring Summary |
| First Quarter |
| San Diego Touchdown - 3-yard run by LaDainian Tomlinson. (Nate Kaeding extra point is good). |
| Second Quarter |
| Pittsburgh Safety - Marcus McNeill tackled in the end zone by James Harrison. |
| Pittsburgh Field Goal - 21-yarder by Jeff Reed. |
| Third Quarter |
| Pittsburgh Field Goal - 41-yarder by Jeff Reed. |
| Fourth Quarter |
| San Diego Field Goal - 22-yarder by Nate Kaeding. |
| Pittsburgh Field Goal - 32-yarder by Jeff Reed. |
| Final Team Statistics | ||
| Statistics | San Diego | Pittsburgh |
| First Downs | 16 | 24 |
| Rushes-yards | 22-66 | 28-124 |
| Passing yards | 159 | 308 |
| Return yards | 147 | 286 |
| Passing (Att-Comp-Int) | 26-15-2 | 41-31-0 |
| Punts-Average | 2-43.5 | 4-31.0 |
| Penalties-Yards | 2-5 | 13-115 |
| Time of Possession | 23:29 | 36:31 |
| Individual Statistics | |
| Rushing | |
| San Diego | LaDainian Tomlinson 18-57, Philip Rivers 1-5, Mike Tolbert 2-4, Darren Sproles 1-0 |
| Pittsburgh | Willie Parker 25-115, Gary Russell 2-10, Mewelde Moore 1--1 |
| Passing | |
| San Diego | Philip Rivers (15-26), Yards: 159, Sacked: 2, TD: 0 |
| Pittsburgh | Ben Roethlisberger (31-41), Yards: 308, Sacked: 4, TD: 0 |
| Receiving | |
| San Diego | LaDainian Tomlinson 3-40, Chris Chambers 3-21, Malcolm Floyd 2-29, Vincent Jackson 2-25, Antonio Gates 2-10, Brandon Manumaleuna 1-17, Darren Sproles 1-9, Legedu Naanee 1-8 |
| Pittsburgh | Hines Ward 11-124, Matt Spaeth 6-55, Santonio Holmes 5-63, Mewelde Moore 5-33, Nate Washington 2-14, Sean McHugh 1-15, Willie Parker 1-4 |
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