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Johnny Tapia, boxing champ, dead at 45

| Sunday, October 19, 2008 | |||||
| Final | 1 | 2 | 3 | 4 | Score |
| San Diego | 7 | 0 | 7 | 0 | 14 |
| Buffalo | 3 | 10 | 7 | 3 | 23 |
| Wrap | |||||
| Scoring Summary |
| First Quarter |
| Buffalo Field Goal - 38-yarder by Rian Lindell. |
| San Diego Touchdown - 14-yard pass from Philip Rivers to Malcolm Floyd. (Nate Kaeding extra point is good). |
| Second Quarter |
| Buffalo Touchdown - 2-yard pass from Trent Edwards to Lee Evans. (Rian Lindell extra point is good). |
| Buffalo Field Goal - 27-yarder by Rian Lindell. |
| Third Quarter |
| San Diego Touchdown - 12-yard pass from Philip Rivers to Vincent Jackson. (Nate Kaeding extra point is good). |
| Buffalo Touchdown - 9-yard run by Marshawn Lynch. (Rian Lindell extra point is good). |
| Fourth Quarter |
| Buffalo Field Goal - 44-yarder by Rian Lindell. |
| Final Team Statistics | ||
| Statistics | San Diego | Buffalo |
| First Downs | 15 | 22 |
| Rushes-yards | 17-72 | 32-109 |
| Passing yards | 208 | 261 |
| Return yards | 191 | 261 |
| Passing (Att-Comp-Int) | 29-22-1 | 30-25-0 |
| Punts-Average | 3-37.3 | 2-52.5 |
| Penalties-Yards | 5-35 | 5-35 |
| Time of Possession | 24:31 | 35:29 |
| Individual Statistics | |
| Rushing | |
| San Diego | LaDainian Tomlinson 14-41, Vincent Jackson 1-31, Darren Sproles 1-1, Philip Rivers 1--1 |
| Buffalo | Marshawn Lynch 19-70, Fred Jackson 9-33, Trent Edwards 4-6 |
| Passing | |
| San Diego | Philip Rivers (22-29), Yards: 208, Sacked: 2, TD: 2 |
| Buffalo | Trent Edwards (25-30), Yards: 261, Sacked: 0, TD: 1 |
| Receiving | |
| San Diego | LaDainian Tomlinson 6-26, Malcolm Floyd 4-65, Antonio Gates 4-55, Vincent Jackson 4-42, Legedu Naanee 2-7, Brandon Manumaleuna 1-8, Darren Sproles 1-5 |
| Buffalo | Lee Evans 8-89, Robert Royal 4-53, Marshawn Lynch 4-22, Josh Reed 3-32, Fred Jackson 3-28, Roscoe Parrish 2-19, Derek Schouman 1-18 |
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