| Scoring Summary |
| First Quarter |
| Buffalo Touchdown - 7-yard pass from Trent Edwards to Robert Royal. (Rian Lindell kick). 5:03 remaining. |
| Second Quarter |
| Buffalo Touchdown - 13-yard pass from Trent Edwards to Robert Royal. (Rian Lindell kick). 9:43 remaining. |
| Pittsburgh Touchdown - 40-yard pass from Ben Roethlisberger to Santonio Holmes. (Jeff Reed kick). 6:26 remaining. |
| Third Quarter |
| Buffalo Field Goal - 43-yarder by Rian Lindell. 9:33 remaining. |
| Pittsburgh Touchdown - 6-yard run by Rashard Mendenhall. (Jeff Reed kick). 1:51 remaining. |
| Buffalo Touchdown - 95-yard kickoff return by Leodis McKelvin. (Rian Lindell kick). 1:38 remaining. |
| Fourth Quarter |
| Pittsburgh Touchdown - 47-yard run by Dennis Dixon. (Jeff Reed kick). 4:31 remaining. |
| Individual Statistics |
| Rushing |
| Pittsburgh |
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| Buffalo |
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| Passing |
| Pittsburgh |
D.Dixon 6-15-0, 79 yards., B.Roethlisberger 9-11-1, 142 yards and 1 touchdown., B.Leftwich 5-11-0, 41 yards. |
| Buffalo |
T.Edwards 9-11-0, 104 yards and 2 touchdowns., J.Losman 4-5-0, 19 yards., M.Baker 1-2-0, 3 yards. |
| Receiving |
| Pittsburgh |
D.Baker 3-57, H.Ward 3-48, W.Reid 3-21, S.Holmes 2-53, N.Washington 2-30, M.Spaeth 2-23, L.Sweed 2-9, M.Moore 1-14, W.Parker 1-4, B.Latsko 1-3. |
| Buffalo |
L.Evans 3-55, F.Jackson 3-10, R.Royal 2-20, R.Parrish 2-19, M.Lynch 1-8, D.Wright 1-6, F.Huggins 1-5, J.Evans 1-3. |
