| Scoring Summary |
| First Quarter |
| San Francisco Field Goal - 32-yarder by Joe Nedney. |
| Philadelphia Touchdown - 1-yard run by Correll Buckhalter. (David Akers extra point is good). |
| Second Quarter |
| Philadelphia Touchdown - 2-yard pass from Donovan McNabb to Hank Baskett. (David Akers extra point is good). |
| Philadelphia Field Goal - 19-yarder by David Akers. |
| Third Quarter |
| San Francisco Touchdown - 6-yard run by Frank Gore. (Joe Nedney extra point is good). |
| San Francisco Field Goal - 29-yarder by Joe Nedney. |
| Fourth Quarter |
| Philadelphia Touchdown - 2-yard pass from Donovan McNabb to L.J. Smith. (David Akers extra point is good). |
| Philadelphia Field Goal - 38-yarder by David Akers. |
| Individual Statistics |
| Rushing |
| Philadelphia |
Correll Buckhalter 18-93, Lorenzo Booker 1-5, Donovan McNabb 1-4, DeSean Jackson 1-1 |
| San Francisco |
Frank Gore 19-101, J.T. OSullivan 3-31, Michael Robinson 1-5, DeShaun Foster 3-4, Delanie Walker 1--10 |
| Passing |
| Philadelphia |
Donovan McNabb (23-36), Yards: 280, Sacked: 0, TD: 2 |
| San Francisco |
J.T. OSullivan (17-30), Yards: 199, Sacked: 3, TD: 0 |
| Receiving |
| Philadelphia |
Correll Buckhalter 7-85, DeSean Jackson 6-98, Hank Baskett 4-38, Greg Lewis 3-38, Jason Avant 1-17, L.J. Smith 1-2, Dan Klecko 1-2 |
| San Francisco |
Vernon Davis 6-75, Arnaz Battle 3-39, Frank Gore 3-16, Isaac Bruce 2-28, Josh Morgan 1-25, Michael Robinson 1-12, Allen Rossum 1-4 |
