| Scoring Summary |
| First Quarter |
| San Diego Touchdown - 81-yard pass from Philip Rivers to Darren Sproles. (Nate Kaeding extra point is good). |
| Baltimore Touchdown - 5-yard run by Willis McGahee. (Steven Hauschka extra point is good). |
| Second Quarter |
| Baltimore Touchdown - 3-run by Willis McGahee. (Steven Hauschka extra point is good). |
| San Diego Field Goal - 22-yarder by Nate Kaeding. |
| Third Quarter |
| Baltimore Touchdown - 9-yard pass from Joe Flacco to Todd Heap. (Steven Hauschka extra point is good). |
| San Diego Touchdown - 35-yard pass from Philip Rivers to Vincent Jackson. (Nate Kaeding extra point is good). |
| Fourth Quarter |
| San Diego Field Goal - 25-yarder by Nate Kaeding. |
| Baltimore Field Goal - 33-yarder by Steven Hauschka. |
| Individual Statistics |
| Rushing |
| Baltimore |
Willis McGahee 15-79, Ray Rice 8-36, LeRon McClain 4-12, Joe Flacco 5-3 |
| San Diego |
Darren Sproles 10-26, Michael Bennett 4-19, Philip Rivers 4-10, Jacob Hester 2-3, Legedu Naanee 1--5 |
| Passing |
| Baltimore |
Joe Flacco (17-26), Yards: 190, Sacked: 1, TD: 2, Mark Clayton (1-1), Yards: 0, Sacked: 0, TD: 0 |
| San Diego |
Philip Rivers (25-45), Yards: 436, Sacked: 2, TD: 2 |
| Receiving |
| Baltimore |
Ray Rice 5-46, Kelley Washington 4-58, Derrick Mason 3-31, LeRon McClain 2-16, Willis McGahee 2-10, Mark Clayton 1-20, Todd Heap 1-9 |
| San Diego |
Darren Sproles 7-124, Vincent Jackson 6-141, Antonio Gates 5-78, Chris Chambers 2-30, Michael Bennett 2-3, Malcolm Floyd 1-45, Legedu Naanee 1-8, Brandon Manumaleuna 1-7 |