The end section of the meteorite, packed with olivine and chromite ovoid crystals, will join other meteorites, fossil specimens and insects preserved in amber on the auction block, a release from Heritage Auctions said Monday.
"The specimens in this sale represent some of the finest fossils, meteorites and natural history items I have had the privilege to handle," Heritage Auctions' Craig Kissick said. "This auction will appeal to everyone fascinated by natural history and truly has something for everyone -- even those new to this collecting genre."
The martian specimen, part of a meteor jettisoned off Mars's surface after it was struck by an asteroid, weights 1.37 pounds, the auction house said.
Meteorites from Mars are among the most exotic substances on Earth and less than 300 pounds are known to exist, it said.
The Nature & Science Signature Auction will be June 2.