The announcement was made Friday by the World Meteorological Organization, which decides on storm names, OurAmazingPlanet reported.
Storm names decided on by the WMO run on a seven-year cycle in the Atlantic Basin and eastern North Pacific Basin, unless retired for causing a considerable amount of casualties or damage.
Irene is the 76th hurricane name to be retired from the Atlantic list since 1954, the National Oceanic and Atmospheric Administration said in a statement.
Irene will be replaced on the list by "Irma."
Irene became a hurricane on Aug. 22, 2011, and intensified to a Category 3 hurricane on Aug. 24 before gradually weakening to a Category 1 when it made landfall in North Carolina Aug. 27.
Irene was the first hurricane to make landfall in the United States in three years.