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New theory addresses frozen Earth paradox
NEW YORK, June 3 (UPI) -- Mount Sinai School of Medicine scientists in New York say they've developed a gene therapy that's safe and effective in reversing advanced heart failure.
The researchers said the therapy, called Mydicar, is designed to stimulate production of an enzyme that enables the failing heart to pump more effectively. In a Phase II study, injection of the gene SERCA2a through a routine, minimally invasive cardiac catheterization was safe and showed clinical benefit in treating and decreasing the severity of heart failure.
"SERCA2a met the primary endpoints and appears to be safe and effective in people with advanced heart failure," said Dr. Jill Kalman, a trial investigator and director of the medical school's cardiomyopathy program. "There is a significant unmet need for treatments in this patient population, and these data indicate SERCA2a is a promising option for them."
The data was presented this week in Berlin during the Heart Failure Congress of the European Society of Cardiology.
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MONTREAL, June 1 (UPI) --
Police in Montreal Friday identified a man who was killed and dismembered as a Chinese university student and said the suspect in the case may be in France.
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NEW YORK, June 1 (UPI) --
American superhero Green Lantern will be revealed as gay in the next edition of "Earth 2," DC Comics announced Thursday.
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MIAMI, June 1 (UPI) --
U.S. forecasters say a new statistical model will help determine a hurricane's strength and size as the official 2012 Atlantic hurricane season gets under way.
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HOLMES BEACH, Fla., June 1 (UPI) --
Employees at a Florida grocery store restrained a Cuban sandwich thief by sitting on him until authorities arrived, police say.
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