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New therapy may fight rheumatoid arthritis

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Published: Jan. 28, 2010 at 12:01 PM
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CHICAGO, Jan. 28 (UPI) -- Northwestern University scientists say they've invented a non-toxic drug that might be able to halt or even reverse rheumatoid arthritis.

Feinberg School of Medicine Associate Professor Harris Perlman said the molecule he and his team invented is an imitation of a suicide molecule that floats undetected into overactive immune cells responsible for the disease.

The scientists said the approach was tested on mice and doesn't carry the health risks of current treatments.

"This new therapy stopped the disease cold in 75 percent of the mice," Perlman said. "The best part was we didn't see any toxicity. This has a lot of potential for creating an entirely new treatment for rheumatoid arthritis."

The study is reported in the February issue of the journal Arthritis & Rheumatism.

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