Schizophrenic mouse developed

Dec. 30, 2009 at 2:40 PM

AUGUSTA, Ga., Dec. 30 (UPI) -- The development of schizophrenic mice should improve understanding and treatment of the disorder in humans, scientists in Georgia said.

Researchers at the Medical College of Georgia have bred a strain of schizophrenic mice by reducing the inhibition of brain cells involved in complex reasoning and social behavior.

To create the mice, the scientists altered a gene for schizophrenia, ErbB4.

"We believe the mouse, which exhibits some of the same aberrant behavior as patients with this disorder, will help identify better therapies," said Dr. Lin Mei, a developmental neurobiologist.

Anti-psychotic drugs already on the market are to be used on the mice to determine more effective treatments, Mei said in a release Tuesday.

It is the first time that scientists have been able to develop an animal model for the disorder, which affects about 1 percent of the U.S. population.

Related UPI Stories
Latest Headlines
Trending News
Astronomers spot strange ripples emanating from star
8 things you didn't know about baby gorillas
New study details formation of Earth's inner core
Varying walking speeds can help you lose weight
Doctors develop faster diagnostic test for blood infections