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FDA approves hereditary angioedema drug

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Published: Dec. 3, 2009 at 7:56 AM
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WASHINGTON, Dec. 3 (UPI) -- The U.S. Food and Drug Administration says it has approved a drug called Kalbitor to treat people suffering from hereditary angioedema.

The FDA said the rare genetic disease causes a sudden and potentially life-threatening fluid buildup due to a defect in a blood protein that helps regulate how certain immune system and blood clotting pathways function. Doctors said decreased function of the protein can lead to rapid and serious swelling of the face or other parts of the body, which may result in excruciating abdominal pain, nausea, permanent disfigurement, disability or death by suffocation.

Kalbitor (ecallantide) is the second drug marketed in the United States to treat the disease, the FDA said. Kalbitor is a liquid that is intended to be injected under the skin by a doctor for patients 16 and older.

The drug is marketed by the Dyax Corp. of Cambridge, Mass.

© 2009 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.

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