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Long recovery from mass extinction seen
LA JOLLA, Calif., Oct. 19 (UPI) -- U.S. scientists say they've been able to dramatically improve the creation of stem cells from human adult tissue without using embryonic cells.
The researcher team, led by the Scripps Research Institute, said its new technique that uses three small drug-like chemicals is 200 times more efficient than, and twice as fast as, conventional methods for transforming adult human cells into stem cells.
"Both in terms of speed and efficiency, we achieved major improvements over conventional conditions," said Scripps Research Associate Professor Sheng Ding, who led the study. "This is the first example in human cells of how reprogramming speed can be accelerated. I believe that the field will quickly adopt this method, accelerating (stem cell) research significantly."
In addition to its significant practical advantages, the scientists said their technique deepens the understanding of the biology behind the transformation of adult human cells into stem cells.
The findings are reported in the early online edition of the journal Nature Methods.
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