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Molecular origin of stem cells uncovered

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Published: Jan. 9, 2009 at 5:08 PM
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PHILADELPHIA, Jan. 9 (UPI) -- U.S. researchers say they've identified the origin of bone marrow stem cells in a mouse embryo.

Nancy Speck of the University of Pennsylvania School of Medicine said the findings, published online in the journal Nature, may help researchers in their effort to manipulate embryonic stem cells to generate new blood cells for therapy.

Hematopoietic -- or blood -- stem cells found in the bone marrow of adult mammals generate all of the blood cell types of the body.

"The ultimate goal for stem cell therapies is to take embryonic stem cells and push them down a particular lineage to replace diseased or dead cells in human adults or children," Speck, lead author of the paper, said Friday in a release.

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