Using zebrafish that share genetics similar to humans, researchers discovered two enzymes that, when combined, could be involved in the earliest stages of cancer, the Salt Lake City-based Institute announced Wednesday.
Genetically manipulating the enzymes could lead to therapies that target tumors in their earliest stage, said David Jones, a senior director at Huntsman.
"We could conceivably reactivate a completely normal gene in a tumor cell -- a gene that could prevent the growth of a tumor if reactivated," Jones said.
The enzymes appear to trigger an "on-and-off switch" for genes that could could cancer and numerous other diseases and birth defects, said the research published in the Dec. 26 issue of Cell.
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