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X-ray spacecraft to search for black holes
ROCHESTER, Minn., June 4 (UPI) -- A U.S. study finds use of low doses of an epileptic seizure medication can significantly reduce the occurrence of hot flashes in prostate cancer patients.
The North Central Cancer Treatment Group researchers based at the Mayo Clinic found use of the drug gabapentin that's also used to treat nerve pain caused by shingles substantially reduces hot flashes in men undergoing anti-hormonal treatment, or androgen-deprivation therapy, for prostate cancer.
The investigators found gabapentin cut the frequency and intensity of hot flashes up to 46 percent in men receiving androgen deprivation therapy.
"To my knowledge, this is the first non-hormonal treatment of hot flashes in men, where results from a placebo-controlled trial are positive enough to support that a non-hormonal medication can be used to help some of our patients," lead investigator Dr. Charles Loprinzi said.
The results of the 223-patient, placebo-controlled Phase III clinical trial were presented during the weekend in Chicago at the 2007 meeting of the American Society of Clinical Oncology.
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