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Genetic marker linked with prostate cancer

EVANSTON, Ill., May 21 (UPI) -- U.S. medical scientists have linked a recently identified genetic marker with a highly aggressive form of prostate cancer.

Northwestern University researchers said their finding will aid the development of a simple blood test to predict who is susceptible to the aggressive cancer. Also, knowing which patients carry the genetic marker will guide physicians in determining their treatment plans.

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The Northwestern researchers found prostate cancer patients who carry the genetic marker -- called 8q24 -- are 40 percent more likely to have a close family member with prostate cancer. In contrast, patients without the marker have a 20 percent chance.

At least 30 percent of African-American men with prostate cancer carry the genetic marker, compared with about 15 percent of men of European ancestry. Men who carry the genetic marker have a 60 percent increase in risk of the disease.

The study's co-principal investigator, Dr. Brian Helfand of Northwestern's Feinberg School of Medicine, presented the research Sunday in Anaheim, Calif., during the annual meeting of the American Urological Association.

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