facebook
twitter
rss
account
search
search
 

Nanoparticles used to track cells

March 27, 2007 at 11:15 AM   |   Comments

ST. LOUIS, March 27 (UPI) -- U.S. scientists have developed a technique using magnetic resonance imaging and nanoparticles to track cells injected into mice.

Developed in the laboratories of Drs. Samuel Wickline and Gregory Lanza at the Washington University School of Medicine, the study suggests fluorine-laced nanoparticles might soon allow physicians to directly track cells involved in medical treatments by using unique signatures from the ingested nanoparticle beacons.

The study's lead author, doctoral student Kathryn Partlow, said perfluorocarbon nanoparticles were used to label endothelial progenitor cells taken from human umbilical cord blood. The researchers believe such nanoparticle-labeled stem cells could be used to monitor tumors and diagnose and treat cardiovascular problems.

The nanoparticles contain a fluorine-based compound that can be detected by MRI scanners. Fluorine is most commonly known for being an element included in fluoride toothpastes.

Wickline, who heads the Siteman Center of Cancer Nanotechnology Excellence at the university, said the technology offers significant advantages over other cell-labeling technologies under development.

The research is to be detailed in the June issue of The FASEB Journal, a publication of the Federation of American Societies for Experimental Biology.

© 2007 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Most Popular
1
Antarctic fish have antifreeze in their veins Antarctic fish have antifreeze in their veins
2
SpaceX breaks ground on commercial launch site in Texas SpaceX breaks ground on commercial launch site in Texas
3
Android phones to join iPhone in saying no to the police Android phones to join iPhone in saying no to the police
4
Populist science: Pluto is a planet Populist science: Pluto is a planet
5
Watch India insert its Mars orbiter live online Watch India insert its Mars orbiter live online
Trending News
Video
x
Feedback