facebook
twitter
rss
account
search
search
 

AIDS vaccine design: Closer to reality

Feb. 14, 2007 at 4:37 PM   |   Comments

BETHESDA, Md., Feb. 14 (UPI) -- U.S. scientists have generated an atomic picture of part of the human immunodeficiency virus in a move that could greatly help AIDS vaccine design.

The researchers, led by a team at the National Institute of Allergy and Infectious Diseases in Bethesda, Md., say the atomic-level picture of a key portion of an HIV surface protein images it as it looks when bound to an infection-fighting antibody.

Unlike much of the constantly mutating virus, that protein component is stable and -- more importantly, say the researchers -- appears vulnerable to attack from a specific antibody known as b12 that can broadly neutralize HIV.

The research team was led by Peter Kwong of the institute's Vaccine Research Center in collaboration with investigators from the Dana-Farber Cancer Institute in Boston and The Scripps Research Institute in La Jolla, Calif.

"This finding could help in the development of an HIV vaccine capable of eliciting a robust antibody response," said Dr. Anthony Fauci, the institute's director.

The research is outlined in the journal Nature.

© 2007 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.
Most Popular
1
Next-generation space suits will be like second skin Next-generation space suits will be like second skin
2
MAVEN space probe to reach Mars this weekend MAVEN space probe to reach Mars this weekend
3
Ship sunk off coast of Texas to create artificial reef Ship sunk off coast of Texas to create artificial reef
4
NASA says they found smallest known galaxy with a black hole NASA says they found smallest known galaxy with a black hole
5
U.N. Secretary General Ban Ki-moon to join climate march U.N. Secretary General Ban Ki-moon to join climate march
Trending News
Video
x
Feedback