Antidepressant similar in effectiveness

WASHINGTON, Jan. 29 (UPI) -- A U.S. study finds the most commonly prescribed antidepressants are similar in effectiveness, but with varying possible side effects.

The U.S. Department of Health and Human Services study found about six in 10 adult patients receive some relief from the drugs, but experience at least one side effect.

The analysis, by the department's Agency for Healthcare Research and Quality, was based on a review of nearly 300 studies of second-generation antidepressants. It showed patients who don't respond to one of the drugs often try another medication within the same class. About one in four of those patients recover, according to the review.

"Second-generation antidepressants provide hope for many of the millions of Americans who struggle with depression," said Dr. Carolyn Clancy, the agency's director. "But often trying to find the right drug is trial and error, and in many cases relief is temporary or comes with serious side effects. It's clear we need more evidence to help patients and their doctors make the best choices."

The full report can be found at http://effectivehealthcare.ahrq.gov