Study: Learning process slows Alzheimer's

IRVINE, Calif., Jan. 24 (UPI) -- A U.S. study suggests the process of learning can slow the development of two brain lesions that are hallmarks of Alzheimer's disease.

University of California-Irvine scientists say their finding indicates older people can help delay the onset of the degenerative disease by keeping their minds active.

The study with genetically modified mice is said to be the first to show short, but repeated, learning sessions can slow a process known for causing the protein beta amyloid to clump in the brain and form plaques. Those plaques disrupt communication between cells and lead to symptoms of Alzheimer's disease.

"This study shows learning can delay the progression of Alzheimer's neuropathology in mice genetically engineered to develop this insidious disorder, and learning also delays the cognitive decline," said Frank LaFerla, professor of neurobiology and behavior and co-author of the study. "These remarkable findings suggest stimulating the mind with activities such as reading books or completing crossword puzzles may help delay and-or prevent Alzheimer's disease in senior citizens."

The study by LaFerla, Professor James McGaugh, and postdoctoral researchers Kim Green and Lauren Billings, appears in the Journal of Neuroscience.