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Omega-3 fatty acids inhibit liver cancer

PITTSBURGH, April 4 (UPI) -- Two studies at the University of Pittsburgh suggest that omega-3 fatty acids inhibit the growth of liver cancer.

The first study looked at the effect and mechanism of omega-3 and omega-6 polyunsaturated fatty acids in human hepatocellular carcinoma cells. Hepatocellular carcinomas account for 80 percent to 90 percent of liver cancers, and patients are usually dead within six months of diagnosis.

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Omega-3 fatty acids are found in fish oils and some seeds and nuts.

Researchers treated carcinoma cells with one of two different omega-3 fatty acids or an omega-6 acid. They found that both omega-3 fatty acids inhibited cell growth, with the effect dependent on the dose, while the omega-6 fatty acid did not.

The researchers also studied cholangiocarcinoma tumor cells. Cholangiocarcinoma is an aggressive form of liver cancer with a high mortality rate.

They got similar results when they treated the cells with omega-3 and omega-6 fatty acids.

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