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The gene that starts puberty is identified

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Published: Oct. 23, 2003 at 4:39 PM
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WASHINGTON, Oct. 23 (UPI) -- Researchers have reportedly identified a gene that signals the beginning of puberty in human beings, as well as in mice.

Science Daily magazine reported Thursday the study, funded in part by the National Institute of Child Health and Human Development, suggests without a functioning copy of the gene, both humans and mice appear to be unable to enter puberty normally.

The newly identified gene, known as GPR54, also appears necessary for normal reproductive functioning in human beings.

The director of the institute, Dr. Duane Alexander, told Science Daily: "The discovery of GPR54 is an important step in understanding the elaborate sequence of events needed for normal sexual maturation. Findings from this study may lead not only to more effective treatments for individuals who fail to enter puberty normally, but may provide insight into the causes of other reproductive disorders as well."

The study appears in the October 23 issue of the New England Journal of Medicine.

Topics: Duane Alexander
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