When police responded to the Naylor home of Bobby Leonard on Saturday, they found his wife Carolyn "laying on the front porch covered in blood."
According to Ripley County Cpl. Earl Wheetley, a man was holding a towel on the alleged victim's shoulder.
Wheetley was told the victim and her husband had been arguing and then he shot her.
The 59-year-old suspect was in the trailer and he asked whether his wife was dead after Wheetley handcuffed him.
"I asked Bobby what happened, and he stated: 'I got tired of her and shot her,'" Wheetley said.
The woman was flown to a Tennessee hospital to be treated for her wound.
"Last I heard, she was in stable condition," Sheriff Ron Barnett told the Southeast Missourian.