The 18-wheeler crashed early Thursday; there were no injuries, but the truck's cargo -- 40,000 pounds of limes -- went flying all over the interstate, the San Antonio Express-News reported.
The highway was shutdown into the afternoon for removal and cleanup of the limes.
"Major accident 37 NB and SB to 10 WB closed; 10 WB traffic will use 10 EB to Pine Exit and Turnaround," said a tweet from the Texas Department of Transportation.
There was no immediate word on what caused the crash.
Man spent 15 hours in jail for plugging electric car into an outlet at a school
Texas principal bans speaking Spanish, stirs controversy