The seller, who goes by the name Jack Mord, said the photo depicts a man nearly identical to the Oscar-winning actor, the New York Daily News reported Monday.
"Personally, I believe it's him and that he is some sort of walking undead/vampire, etcetera, who quickens/reinvents himself once every 75 years or so," the online seller wrote on the eBay posting. "150 years from now, he might be a politician, the leader of a cult or a talk show host.
"My theory is that he allows himself to age to a certain point, maybe 70, 80 or so, then the actor 'Nicolas Cage' will 'die' ... but in reality, the undead vampire 'Nicolas Cage' will have rejuvenated himself and appeared in some other part of the world, young again, and ready to start all over."
Mord said he will allow potential buyers to verify the authenticity of the photo, which was taken by Civil War-era photographer Professor G.B. Smith.
"Any serious potential buyer will be allowed to have a photo expert of their choice examine the original photograph before any money changes hands," he wrote.