Marilyn Michose, 46, of Danbury, Conn., was wandering around the lobby just after 9 a.m. Saturday speaking "gobbledygook," a hotel maid said, just before a security guard spotted a .25-caliber semiautomatic pistol poking out of her pocket, the New York Post reported.
Michose told hotel staff she wanted to put her valuables in a safe at the Park Avenue hotel, the report said.
After security chased her into an empty bar, she surrendered and gave up the unloaded weapon, the New York Daily News said.
Michose's 87-year-old mother Joy said her daughter suffers from Lyme disease and is on a medication that makes her manic.
Michose, an occupational therapist who is on disability, drove to New York and checked into the hotel to visit a friend and started acting erratically Friday night, her mother said.