"It has been suggested that acetaldehyde is one of the key toxic chemicals that influences the severity of a hangover," Schaefer said. "So any deterioration in ADH (aldehyde dehydrogenase) levels would contribute to worse hangovers."
Schaefer said cheap alcoholic beverages can also influence the severity of a hangover due to the higher presence of congeners, the "chemical soup" resulting from the fermentation and distillation processes.
"The more expensive liquors are often filtered and triple or more distilled -- thus, cleaner alcohol, less junk," Schaefer said.
"As we age, we may be unable to avoid chemical changes that could be wrecking the efficiency of our liver, and we should avoid lousy intoxicants, as they are guaranteed to cause digestive or metabolic discomfort," he said.
