Investigators said the host of the party on the West Side allowed the man to enter early Sunday to avoid a confrontation, but the party-crasher became angry when revelers mocked his bottle of Nuvo, the San Antonio Express-News reported Monday.
An incident report said party guests told the man the "bottle looked like a lipstick cap, indicating that (he) is or was a homosexual, which made (him) upset."
Police said the man left the party and returned with a handgun, which he first fired into the air, then aimed shots at guests in the back yard.
One of the shots struck James Collins, 23, in the lower abdomen at about 2:15 a.m.
The suspect fled the party and Collins was taken to University Hospital in stable condition.