The card bearing a digitally added Bush in the stands and Mantle in the dugout went right past the proofreaders and is selling for $2 on eBay, the New York Daily News reported Tuesday.
It could possibly fetch up to $500 if a collector gets both the president and Jeter to autograph it, an expert said.
Once the cards came back from the printer, "We couldn't do anything but laugh," Topps spokesman Clay Luraschi told the Daily News.
Jeter told the newspaper he hadn't heard anything about the card and a White House spokesman declined to comment. The White House has to give permission any time the president's likeness is used for commercial purposes, the Daily News noted.
Topps has not decided whether the interlopers will be erased and a new card inserted into boxed sets.