The scene unfolded Saturday at Flav's Variety store, where store manager James Foster encourages regular customers to watch games on a wall-mounted television, the Toledo Blade reported Monday.
At half-time in the Ohio State-Michigan game, one of the fans suggested playing the game's final score as a Pick 4 ticket.
Foster said he laughed when six fans scrambled to buy tickets when the game ended at 7:13 p.m., 16 minutes before the draw.
He's said he's kicking himself now for not spending $1 too, the draw came up 4, 2, 3 and 9, the newspaper said. The odds of those numbers turning up in that combination -- or any combination -- are 10,000 to 1, lottery officials said.
The odds of them matching the score of a just-finished football game, however, weren't published.