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Huge database for kidney disease research

Published: Dec. 29, 2004 at 5:02 PM
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BETHESDA, Md., Dec. 29 (UPI) -- Three U.S. scientific groups have formed the largest collection of biosamples and data for research on genetic causes of kidney disease in type 1 diabetics.

The National Institutes of Health, Juvenile Diabetes Research Foundation, and Centers for Disease Control and Prevention said Wednesday the Genetics of Kidneys in Diabetes collection has nearly 10,000 DNA, serum, plasma and urine samples, plus genetic and clinical data from more than 1,700 adults with type 1 diabetes in the United States and Canada.

Of those, 818 have had diabetes at least 10 years and have developed kidney disease, a common complication of diabetes. The other 893 have had diabetes at least 15 years but do not have kidney disease. Also in the collection are data and samples from 1,096 parents.

Researchers can apply for DNA, extensive clinical data and some genetic data from the collection at gokind.org/access; serum, plasma and urine samples will be made available later.

Methods of treatment, insulin doses, complications, smoking history and other data have been documented for all participants. Also, DNA has been genotyped for genes well-known to predispose to type 1 diabetes.



© 2004 United Press International, Inc. All Rights Reserved.
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