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American actress Renee Zellweger attends the premiere of "Leatherheads" at Odeon, Leicester Square in London on April 8, 2008. (UPI Photo/Rune Hellestad)
The television movie, which is to star Harry Connick, Jr., will reunite Zellweger with Craig Zadan and Neil Meron, the executive producers of Zellweger's acclaimed movie musical, "Chicago."
"Living Proof" is the real-life story about a UCLA doctor's quest to develop the breast cancer drug Herceptin 2.
Lifetime said the movie is scheduled to air in October as the programming centerpiece of the network's public awareness campaign, "Stop Breast Cancer For Life."
The film is to be shot in Connick's hometown of New Orleans.
This project marks Zellweger's first television venture, as well as a reunion with Connick, with whom she recently completed filming the feature, "Chilled in Miami."